Actualización en lupus neuro-psiquiátrico con énfasis en déficit cognitivo.

Tomás León, Carla Henríquez, Jorge Calderón, Loreto Massardo

Resumen


 

AN UPDATE ON NEUROPSYCHIATRIC LUPUS WITH EMPHASIS IN COGNITIVE DYSFUNCTION

Patients with systemic lupus erythematosus (SLE) suffer from a number of neuropsychiatric (NP) symptoms throughout their disease affecting them both physically and psychologically. We review herein the nomenclature and case definitions for neuropsychiatric lupus syndromes proposed by the American College of Rheumatology in 1999. We emphasize cognitive dysfunction and discuss etiological hypotheses, especially those related to the presence of antineuronal autoantibodies. 


Palabras clave


Autoantibodies; Lupus erythematosus systemic; Neurobehavioral manifestations