La presión arterial es un importante marcador de ateroesclerosis subclínica en niños

Pilar Arnaiz, Luis Villarroel, Salesa Barja, Iván Godoy, Berta Cassis, Angélica Domínguez, Oscar Castillo, Marcelo Farías, Jacqueline Carvajal, Ana Cristina Tinoco, Francisco Mardones

Resumen


ASSOCIATION OF CAROTID INTIMA MEDIA THICKNESS WITH BLOOD PRESSURE AND HDL CHOLESTEROL IN CHILDREN

Background: Cardiovascular risk factors must be controlled since childhood. Aim: To assess the association of carotid intima media thickness (CIMT) with the components of the metabolic syndrome in Children. Material and methods: Cross sectional assessment of 299 children aged 11.5 ± 0.9 years (58% women) with and without metabolic syndrome components. Anthropometric parameters and blood pressure were measured and a blood sample was obtained to measure blood glucose and lipids. CIMT was measured using high resolution ultrasound. Results: Ninety three percent of children were post puberal, 64% were overweight and 25% had metabolic syndrome. Mean and maximum CIMT correlated with systolic blood pressure ( r=0.21 and 0.21 respectively p < 0.01). Children with a CIMT over the 75th percentile had higher blood pressure and lower HDL cholesterol. A stepwise logistic regression accepted both variables as predictors of CIMT with odds ratios for mean CIMT of 1.46 (1.19-1-79) and 0.81(0.7-0.94) per five units of change, respectively. Conclusions: In this group of children systolic blood pressure and HDL cholesterol are associated to CIMT. 


Palabras clave


Blood pressure; Carotid Intima-Media thickness; Child; Cholesterol HDL